Developmental Programming of Fetal Skeletal Muscle and Adipose Tissue Development
نویسندگان
چکیده
منابع مشابه
Developmental Programming of Fetal Skeletal Muscle and Adipose Tissue Development
All important developmental milestones are accomplished during the fetal stage, and nutrient fluctuation during this stage produces lasting effects on offspring health, so called fetal programming or developmental programming. The fetal stage is critical for skeletal muscle development, as well as adipose and connective tissue development. Maternal under-nutrition at this stage affects the prol...
متن کاملFetal programming of skeletal muscle development in ruminant animals.
Enhancing skeletal muscle growth is crucial for animal agriculture because skeletal muscle provides meat for human consumption. An increasing body of evidence shows that the level of maternal nutrition alters fetal skeletal muscle development, with long-term effects on offspring growth and performance. Fetal skeletal muscle development mainly involves myogenesis (i.e., muscle cell development),...
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Skeletal muscle is a highly dynamic and malleable tissue that is able to adapt to different stimuli placed upon it, both during gestation and after birth, ultimately resulting in anatomical changes to muscle fibre composition. Variation in nutrient supply throughout gestation is common, whether in livestock or in the human. The specific effects of maternal nutrition on foetal development are at...
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It is apparent from epidemiological studies that the timing of maternal nutrient restriction has a major influence on outcome in terms of predisposing the resulting offspring to adult obesity. The present review will consider the extent to which maternal age, parity and nutritional restriction at defined stages of gestation can have important effects on fat deposition and endocrine sensitivity ...
متن کاملPROJECT #1. Developmental programming of skeletal muscle: impact of fetal growth retardation on muscle morphology in adult rats
The early-life environment, particularly in the fetus, is now recognised as an important determinant of several adult-onset diseases. Thus, increased frequencies of hypertension, obesity, dyslipidemia and type 2 diabetes, collectively referred to as the ‘Metabolic Syndrome’, have been linked to intrauterine growth retardation (IUGR), an assumed marker of a poor fetal environment. These links ar...
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ژورنال
عنوان ژورنال: Journal of Genomics
سال: 2013
ISSN: 1839-9940
DOI: 10.7150/jgen.3930